CCSVI - Team Brain Flow

About Us

Brain Flow Team is a multidisciplinary group for CCSVI born in 2010. To date, the Team has the greatest experience worldwide in the interventional treatment of CCSVI patients.

Dr. Lupattelli and his Brain Flow Team are based in Rome, at the Research Cardiological Institute GVM Sanità. Team Brain Flow was born in April 2012 by the union of different specialists with the aim to diagnose and treat CCSVI. The team further purpose is to conduct scientific research aimed to definitively validate the CCSVI as a real nosological entity (and likely bounded with multiple sclerosis) as well as to prove its existence in other neurodegenerative diseases. The team is also widely involved in the evaluation of clinical outcomes following treatment of the affected veins by percutaneous balloon angioplasty (PTA).

The first to take care of CCSVI patients was Dr. Tommaso Lupattelli, interventional radiologist and vascular surgeon who in September 2010, began to treat the first patient at Villa Salus in Reggio Emilia, Italy. He graduated in CCSVI diagnosis and treatment at University of Ferrara in 2011. Subsequently, two sonographers, Dr. Giovanni Bellagamba and Dr. Elena Righi became part of the group. In 2012, the team was finally joined by 3 neurologists, Dr Paolo Onorati, Dr.Christian Marcotulli and Dr Claudio Babiloni. Currently these multidisciplinary team is made by radiologists and neuroradiologists , vascular surgeons , cardiologists, sonographers, neurologists and many others (posturologist, medical engineer, dietician, etc.). Currently, Brain Flow Team is one of the the most experienced team for the diagnosis and treatment of CCSVI in the world with a total of 5000 Color Doppler ultrasounds and about 2400 interventional procedures already performed.

The Brain Flow team has progressively developed the technique of Prof Zamboni (the so called liberation treatment), improving it significantly in several aspects. The team also carry out accurate assessments of CCSVI patients by EEG prior to and after angioplasty. Some relevant studies on EEG results are due to be published in the medical literature soon. Team Brain Flow is also involved in different experimental projects designed to assess the effectiveness of endovascular surgery in patients with CCSVI and multiple sclerosis. Recently, a feasibility and safety study on CCSVI treatment conducted in a cohort of 1202 patients has been reported by Dr. Tommaso Lupattelli and his colleagues. The study, which is the greatest study ever reported in the medical literature in terms of number of CCSVI subjects treated, concluded that the percentage of major and minor complications are extremely low after angioplasty, particularly when the interventional radiologist has completed his surgical learning curve (at least 400 cases performed). Of importance, clinical results of the procedure seem strongly related to the interventional radiologist experience in CCSVI treatment.

The Coordinator

*Dott. Tommaso Lupattelli

Specialist in radiology and interventional radiology, specialist in vascular surgery.

Lecturer at the University of Perugia.
ICC GVM SANITÀ Casal Palocco, Roma
Office (Roma): Via Achille Barilatti 54
Office (Milano): Centro medico Col di Lana 2
Website>Scientific Pubblications>

Dr. Tommaso Lupattelli has been interested in interventional radiology since the University. He attended the best Italian and foreign institutes to obtain the final consecration in 2003 where he left Perugia for an important interventionist radiology project in the city of Milan. During these years he has developed qualified skills in endovascular revascularization in diabetic patients and not with severe arterial stenosis-obstructive arterial disease. It also performs endovascular revascularization for steno-obstruction of the carotid, renal, succlavia and other peripheral vascular arteries. He also has a qualified experience in the angioplasty of the venous axis, particularly the jugular-succlavic axis, the iliac vessels caval-azygos system and fistulas and dialysis access. To date, Dr. Tommaso Lupattelli has performed more than 2400 angioplasties in patients with CCSVI. He has held numerous angioplasty courses as a teacher in Europe and abroad, particularly in Mexico and in Lebanon. He has been active in the design and manufacture of some angioplasty materials still used in Europe, Asia and Central America. He is a consultant to some international companies of angioplasty and arterial closure systems productions. He is among the first operators in Italy to carry out the embolization technique of vascular malformations and uterine fibroids, the latter where he has an important case that will be soon published. She also deals with male and female varicocele embolizations. He is the author of several scientific publications on peer rewied journals where he also reported on the implementation of new techniques and materials that then became commonly used, in particular the ONYX in the aneurysm of renal artery or the histoacryl in the aneurysm of liver artery. He also started a project concerning the publication of the first Italian manual on interventionist radiology in two volumes by Tommaso and Luciano Lupattelli.

The Team

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